Sentence examples for indicative of the development from inspiring English sources

Planarians (Dugesia dorotocephala) that were exposed for 1 h to cocaine (80 μM) or to the κ-selective opioid receptor agonist U-50,488H (1 μM) displayed an abstinence-induced withdrawal syndrome, indicative of the development of physical dependence, when they were tested in cocaine- (or U-50,488H) free water, but not when they were tested in cocaine- (or U-50,488H) containing water.

Levels of blood urea nitrogen and creatinine were increased in wild-type and IL-17A−/− mice with CLP-induced sepsis compared with those in the sham group, indicative of the development of SA-AKI.

At 13 18 weeks the db/ db mice showed significant differences in glucose tolerance tests (GTTs), indicative of the development of diabetes (ESM Fig.  1b, c; n = 38 mice, one-way ANOVA p < 0.0001).

They also observed that intermittent locking may be indicative of the development of a disc displacement without reduction which is only rarely accompanied by symptoms of permanent locking [ 8].

Additional studies in animals show there are effects on bone marrow cellularity (hypo- and hypercelluarity) and colony forming stem cells, which are indicative of the development of aplastic anemia (ATSDR, 2007).

- Furthermore, a booster dose of DTPa-HBV-IPV/Hib induced marked increases in antibody concentrations in toddlers who had been born prematurely, indicative of the development of immune memory and effective priming by DTPa-HBV-IPV/Hib.

Although unusual fatigue and irritability as unspecific mood changes are also taken into consideration, to the best of our knowledge, no investigation to date has studied whether a more unspecific symptom picture beyond the known premonitory signs of an acute hyperglycaemia is indicative for the development of T2DM several years before the point of clinical recognition.

As a regrowth is indicative for the development of phage resistant bacteria, this is in sharp contrast with the further increasing phage count (Figure 3C+D).

Here, leukocyte levels greater than 20.21 g/l are indicative for the development of sepsis.

In order to identify biomarkers indicative for the development of cholestasis, significant genes identified in GSEA were subjected to Venn analysis.

It also displays a 2.2- μ m absorption feature indicative of the incipient development of dioctahedral clay minerals.