Sentence examples for indicative of target from inspiring English sources
If subjective confidence could be proven to be indicative of target visibility this result would imply that blindsight - or the ability to rout information from the sensory to the decision making machinery in the absence of consciousness - decreases substantially after a few hundred milliseconds.
Indeed, ponatinib treatment led to a shift in the RIPK3 thermostability curve, indicative of target engagement.
In addition to the correlation with efficacy, systemic exposure of a drug may also correlate with biomarkers indicative of target inhibition.
In other words, even if the change in the relative current response cannot be readily predicted (or correlated accurately with target concentration), the change in the current ratio will be indicative of target binding.
The searches were performed by combining MeSH (Medical Subject Headings) terms that are indicative of acute illnesses of interest (sepsis, bacteraemia), predictive of illness severity (signs, symptoms, clinical predictors, clinical markers) and indicative of target age group (neonates, infants and children).
The selection of 30 mg per week as the dosage for everolimus was based on the results of a phase I study in which single doses of everolimus of up to 30 mg had been shown to be satisfactorily safe and capable of inhibiting a biomarker indicative of target activity (S6K1 activity in peripheral blood mononuclear cells) (O'Donnell et al, 2008).
OXPHOS genes share an expression program distinct from other genes encoding mitochondrial proteins, indicative of targeted nuclear regulation of a mitochondrial sub-process.
Transfections of these constructs, together with a pre miR-6715 expressing vector into HEK293T cells, and measurement of the relative luciferase activity compared to a mutant 3'UTR construct, were indicative of targeting.
It is noteworthy that although Esrp1 RNA levels are not completely absent in the Esrp1 KO RNA-seq samples by FPKM, mapped reads from the RNA-seq data confirmed that these RNAs represent transcripts splicing across the exon 7 9 deletion from exon 6 to exon 10, which would not encode a functional Esrp1 protein and reduced transcript levels are indicative of targeting by NMD.
Since CT values are directly indicative of original target template abundance, we have created four categories into which most qPCR targets seem to fit, namely: 1).
The targeting polymer Eph-PEG-p(CBA-DAH) shows selective uptake by the target cell line, indicative of the targeting properties that will be seen in systemic administration.
