High PTX3 values were associated with several endpoints indicative of severe disease (Table 3).
High PTX3 values were associated with several variables indicative of severe disease.
A fixed heart rate that is unresponsive to moderate exercise, stress, or sleep indicates almost complete cardiac denervation (19) and is indicative of severe CAN.
When animals lack appropriate physical, mental and social stimulation, they can develop what are called "stereotypies", repetitive behavior patterns such as pacing or weaving which are indicative of severe psychological suffering.
Dramatic ER distension is usually an indicative of severe ER stress (Wikstrom et al., 2013).
The liver is of markedly increased echo intensity relative to the renal cortex, indicative of severe steatosis.
Also macroscopically, livers of CCl4-treated rats appeared larger and with a pale and irregular surface indicative of severe hepatocellular damage; representative images are depicted in Fig. 1b.
A transesophageal echocardiography demonstrated markedly worsened dilation of the right ventricle with a very small left ventricle indicative of severe right heart strain.
Intestinal pneumatosis and gas in the mesenteric or portal veins are indicative of severe ischaemia and are usually associated with the thinning rather than thickening of the small bowel wall due to bowel wall necrosis [24].
As discussed above Al and Fe concentrations, which are particularly high in surface rivers during strong rainy seasons like in 2012 (Table 1, Al 0.36 4.4 mg/L, Fe 0.15 1.8 mg/L), are probably indicative of severe water input from the surrounding fields.
This was indicative of severe strain to the cells, some of which most probably died.
