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However, the value of M2 (amount of cPrPGPI-SP colocalizing with MitoTracker) decreased from 0.9 (at 12h after transfection) to 0.4 and 0.1 (24h and 36h after transfection respectively), indicating that the majority of cPrPGPI-SP had lost MitoTracker staining, which is indicative of loss in MMP.
But beyond the direct cost of those jets, it is also indicative of loss of the 'lean-and-mean' culture that used to be in Tesco' DNA.
This is indicative of loss of a chromophoric property, which is caused by alteration of the bonds within adenine.
High levels of these enzymes in the serum may be indicative of loss of the functional integrity of hepatocytes and subsequent leakage of cell contents [40].
Many other locations also showed an amorphous mass of cells indicative of loss of tissue integrity.
Even when RARα was still expressed, we observed in a significant fraction of cells both RA resistance, indicative of loss of RARβ2 function, and aberrant acinar morphogenesis, indicative of loss of CRBP1 function.
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Given that indels are likely to have deleterious effects on protein production and function, the occurrence of indels may be indicative of loss-of-function effects for such genes.
Near-diploid/tetraploid NBTs (n = 13) displayed a wider range of values (0.5 2.7-fold 0.5 2.7-fold of losses and gaindicative a mofe heterogeneous clossespopulandon, as shown by FISH results.
Weight loss, indicative of the loss of inflammatory cells and reduced tissue oedema, signified a reduction of tissue inflammation.
ACLT joints exhibited loss of Safranin O staining indicative of glycosaminoglycan loss, clefts extending into the middle zone and hypocellularity.
As shown in Fig. 4, cells exposed to extracts of WT GBS exhibited a high percentage of cells with reduced TMRE staining, indicative of a loss of mitochondrial membrane potential, approaching the loss of potential observed after treatment with the positive control agent, FCCP.
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