Sentence examples for indicative of deficient from inspiring English sources

Moreover, age-related spatial memory impairment is associated with altered subcellular concentrations of PKCgamma and may be indicative of deficient signal transduction and neuronal plasticity in the hippocampal formation.

High bacterial counts in the peritoneal fluid are indicative of deficient host clearing of bacteria (von Kockritz-Blickwede et al. 2008).

Yeast mutants defective in sterol biosynthesis have multiple small vacuoles, indicative of deficient organelle fusion (Kato and Wickner, 2001; Seeley et al., 2002).

Therefore, the CNS and neuroretina of Cln3 Δex1- mice similarly display defective lysosomes and autophagolysosome structures, both indicative of deficient lysosome-related degradative processes.

Furthermore, increased IgG1 permeability in G3 mTerc−/− brains is indicative of a deficient BBB function.

Because the impaired degradation and accumulation of autophagic substrates was indicative of a deficient autophagic process, we hypothesized that the transport and fusion of endosomes/autophagosomes to lysosomes was impaired.

Similarly, low levels of IL-6 may be indicative of a deficient host immune response, as IL-6 is an important mediator of inflammation and activator of neturophils and has been shown to be required for successful defense against bacterial pathogens, such as Streptococcus pneumoniae (van der Poll et al. 1997) and Listeria monocytogenes (Kopf et al. 1994).

Our data show that H. pylori infection in children from a major Brazilian city is associated with variables indicative of a crowded environment and deficient sanitation/habitation conditions, leading to the conclusion that improvements in hygiene and social conditions may protect children against this infection.

Indeed, we show a decrease in the lung histological injury score and the number of apoptotic cells, indicative of reduced ALI in RIPK3-deficient mice.

In addition, the global 5α-reductase activity, determined by urinary steroid profiling, is increased in STS-deficient males, indicative of a compensatory mechanism counteracting a relatively reduced rate of tissue-specific androgen activation (unpublished data).

This interaction was also observed in CSB-deficient patient cells, indicative of a CSB-independent binding of UVSSA to TC-NER complexes.