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Given that the pretreatment value of Ki67 is a strong prognostic factor and that the arguments above indicate that the change in Ki67 is indicative of benefit from therapy, the 2-week value might be expected to be an indicator of the patient's prognosis on that particular treatment.
Negative SMDs were indicative of benefit, i.e., decreases in depressive symptoms.
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Therefore, by definition, MID-based improvements are indicative of treatment benefit, and could guide physicians in making treatment decisions.
Therefore, treatment of post-MI rats with the ACE inhibitor, ramipril (Ram), provides an ideal model for investigating potential changes in peptide profiles that may be indicative of therapeutic benefits and/or drug induced responses.
This research is indicative of potential benefits for mental health service teams of introducing Peer Worker roles.
Scores of 2 or more were indicative of skin benefits assessed as visibly significant by both the investigator and the subjects.
Those sampled in 2010 gained higher scores on the measures of testing benefits and testing norm than did those sampled in 2000, indicative of greater perceived benefit and a stronger testing norm [ t (1284) = –8.46; P < 0.001 and t (1236) = –11.62; P < 0.001, respectively].
The increased gene expression associated with IFNγ may be indicative of potential therapeutic benefit in reversing post-operative immune suppression.
It was concluded that the presence of an EGFR mutation is not indicative of a survival benefit, but may increase the responsiveness of patients with NSCLC to erlotinib treatment (Tsao et al, 2005).
Other data indicative of a QOL benefit with epoetin alfa treatment are provided by several randomised, controlled and single-arm studies in cancer patients with a variety of malignancies.
Therefore, the comparison would be expected to underestimate any advantage of the current study treatment; and moreover, any improvement with the current study treatment would be more indicative of a true benefit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com