Thus any fluorescent signal in the brain would indicate EB bound to albumin in the parenchyma and not the surrounding vasculature, indicative of BBB breakdown.
At the same time, Mr. Sullivan said his goal was to show his agents that he had confidence in them and understood that the actions of a few rogue agents were not indicative of a breakdown in ethics.
Is this latest gaffe indicative of the breakdown of editorial process in the Age of the Blog?
During acute optic neuritis, a common MRI finding is contrast enhancement of the optic nerve, indicative of BBB breakdown.
The presence of the initial hernia and the high risk of recurrence are indicative of a breakdown in the normal wound healing process.
Interestingly, Bim − / − mice on a mixed 129/Sv X C57BL/6 background develop a systemic lupus erythematosus (SLE -like autoimmune diSLE -likedicautoimmune breakdisease tolerance (Bouindicativel., 1999).
As citrulline levels in ADI-PEG20 treated mice are directly associated with degradation of arginine to citrulline through the enzymatic activity of ADI, rising citrulline levels are indicative of continued breakdown of systemic arginine.
Some of these would be unlikely to encode functional PR since they would lack too many of the protein domains; for example, PRΔ4+6 would lack the nuclear location signal and LBD but has been shown to be present more frequently in malignant than 'normal' breast tissue [ 55], and is perhaps indicative of a breakdown in normal splicing control mechanisms.
Hypoglycemia in turn causes the brain to release glutamate in the brain in levels that are both alarming and that can cause symptoms that are indicative of mental breakdown such as anxiety, depression, panic attacks.
