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To describe clinical characteristics driving repeated blood culture sampling: clinical indications, time interval between cultures, and rates of blood culture-positivity.
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The challenges are confounding by indication, time dependency, and repeated exposure of the intervention and competing risks.
We evaluated DEX indication, time of usage and dosage, necessity of other sedating drugs, and reasons for DEX interruption.
Additional covariates tested when adapting and optimizing the model for children included age, gender, bodyweight, indication, time since treatment start, dose, and CYP4F2 genotype (tested as allele effects).
Whereas microbiological laboratory practice has been highly standardized, shortfalls in the preanalytic procedures in the ICU (that is indication, time-to-incubation, blood volume and numbers of BC sets) have a significant effect on the diagnostic yield.
In all indications, the time to first lymphoma and time to first NMSC did not change with longer follow-up in this analysis.
There are some indications that time preferences for health may be domain independent and distinct from time preferences for monetary rewards.
Mr. Brodsky said there were ample indications this time that the shutdown was an avoidable consequence of economic decisions by the company.
The four premolar extraction protocol frequency decreased gradually while the two maxillary premolar extraction protocol has maintained the same frequency of indications throughout time.
Moreover, it is essential to realize that the patient will change, and may develop different clinical indications over time.
"We don't see any similar indication this time.
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