This association could be largely driven by the correspondence between genetics and drug indications; side effects may tend to occur or be monitored more closely in the organ system of drug action, or side effects may be exaggerated pharmacology effects directly related to the therapeutic effect.
Hospital pharmacists must be able to explain clearly a medication's indications, side effects, and contraindications to patients--and doctors--who may not be at their most coherent.
We extracted the proportion of advertisements that included information on brand name, generic name, indications, side effects, dosage, interactions, precautions and contraindications, warnings and treatment of overdose.
For example, they deliver information about medicines' indications, side effects and contraindications, and offer comparisons between one specific product and another.
A wide variety of imaging techniques is an integral part of modern medicine [ 1], as is the knowledge about indications, side effects and limitations of techniques spanning from bed-side ultrasound over high resolution computed tomography to functional magnetic resonance imaging.
We use this cross-validation procedure to test the contribution of genetics to off-indication side effect prediction (measured as cross-validation AUC) relative to two baselines: the AUC of a model including no genetic information, and the AUC distribution of models with simulated data with permuted gene phenotype relationships.
To design a module that students reacted favorably to on diabetes mellitus medications that increases student retention of medication names (including brand and generic), mechanism of action, indications, side-effects (Black Box Warnings), route (and dose), and aids them in their ability to apply that knowledge to "real-world" patient cases.
This was true even when modeling other predictive variables and excluding potential exaggerated pharmacology (i.e., on-indication side effects).
We also ran these models two ways: using the complete dataset and using a dataset that excluded on-indication side effects, as in the previous enrichment analysis.
Significantly drug-associated off-indication side effects (Fisher's exact one-tailed P < 0.05) were used to compile a dataset of 4275 drug-SE combinations (Supplementary Data 3–5).
