The parameter ni, an indication of sensitivity to equivalence ratio, for stable aromatic precursors exhibits the following rank order: c-C5H6 (4.21) > C3H4 (3.09) > b-C4H6 (2.43) > C4H4 (2.20) > C4H2 (2.16) > C2H2 (1.66).
Each antibody was coupled to a unique bead region so that the mix of captors could be analyzed against each biotinylated tracer individually for specificity to be gauged and a first indication of sensitivity to be noted.
In this early time interval we did not find any indication of sensitivity to the context of a stimulus in a sequential presentation.
In previous papers, we have used values <300 (i.e. a 50% reduction in IndexSUM) as an indication of sensitivity (Knight et al., 2004).
Several groups have investigated the predictive value of DPD as an indication of sensitivity to 5 FU[ 19, 20], suggesting that low levels of intratumoral DPD expression are associated with 5-FU responsiveness.
There was also an indication of sensitivity to the cultural background [F 1,182) = 7.5, P < 0.01], as there was an increase in these scores in the Romanian sample, irrespective of the diagnosis and developmental period.
Several parameters of efficacy can be calculated e.g. IC50 and IC90, however previous ATP-TCA studies have found that a natural logarithmic sum index (IndexSUM) calculated by direct addition of the percentage survival at each concentration tested (Index = 600-Σb3;%Inhibition6.25...200) provides a better indication of sensitivity or resistance to different drugs in different tumour types [ 22].
The IC50 and IC90 were calculated by the trapezoidal rule, and a natural logarithmic sum index (IndexSUM) was obtained by direct addition of the percentage survival at each concentration tested (IndexSUM = 600-Σ (%Inhibition6.25...200) as this has been shown to provide a better indication of sensitivity or resistance to different drugs in different tumour types than other ATP-TCA parameters [ 12].
In the samples that screened positive for HPV infection but were negative in the HPV genotyping assay there were some indications of reduced sensitivity (notwithstanding the high rate of β-globin positivity indicating sample integrity), probably due to the long storage time.
According to him, other indications of chemical sensitivity included "fear of society, fear of being alone, fear of contamination … fear of fears … fear of everything".
