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For a given size, malignant microcalcifications tend to be more irregular, which corresponds to the most important clinical indications of malignancy i.e. linear or branching microcalcifications.
While the carcinomas have clear morphological indications of malignancy, the biological behavior of focal acinar hyperplasia and acinar adenoma is not known.
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Absolute indication of malignancy is extraovarian metastasis.
The presence of many small microcalcifications can be an indication of malignancy.
Detection of field cancerisation by FISH may prove to have a utility in the evaluation of histology-negative biopsies from patients suspected of having prostate cancer, and therefore could aid histopathological evaluation by providing an indication of possible presence of malignancy.
Often the diagnosis is established biochemically before surgery and, although preoperative localisation can be difficult, the biochemical diagnosis provides some indication of the likelihood of malignancy (eg, low with insulinoma), and localisation can be aided by hepatic venous sampling after calcium stimulation.
The data showed that the appearance of many small microcalcifications can be an indication for malignancy.
Therefore, we should not trust morphological findings but immunohistochemistry for some relevant proteins may provide indications of SFT's clinical malignancy.
In 1940 (8%) cases SNOWMED CT codes gave no definitive indication of the primary site of malignancy.
There were significant differences in age at diagnosis, history of malignancy, and indication for imaging between the two groups.
A conclusive preoperative diagnostic method for malignancy of liver tumors should be established; otherwise, clinicians should carefully consider the indication for surgery against the possibility of malignancy.
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