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Particularly, strengthening the designs of these studies could yield useful indications of effectiveness.
Another element of great interest, and arguably the more challenging element of this call for research collaboration, is to seek indications of effectiveness of instruction.
No randomised trials have been reported, but indications of effectiveness have been seen in time trends of mortality, cohort studies and case-control studies [ 38].
Firstly, there is no active treatment control group so that any indications of effectiveness need to be interpreted with caution as we will not know whether possible benefits are a function of this specific treatment or structured treatment in general.
We aim to evaluate key trial parameters, such as recruitment and retention of participants, randomisation, levels of missing data and preliminary indications of effectiveness, to inform calculation of a sample size for powering a full trial.
Similar(54)
Patients could be provided with a low-cost try-out device capable of reliable titration, providing an indication of effectiveness and of patient acceptance of an OAm, although the effect of device shape and size on therapeutic outcome is not yet known.
16 The review's tentative conclusion reports "some indication" of effectiveness with speech and language therapy.
A first indication of effectiveness came indirectly from the seminal meta-analysis by Nunes & Levin 26.
However, it is important to note that this trial will only provide a preliminary indication of effectiveness and that its primary purpose is to assess feasibility and acceptability.
So far, none of these indications of clinical effectiveness have been proved except for osteoarthritis [16 18].
This serves a dual purpose: one is to provide a flavour of the potential results of the meta-analysis; another is to give some absolute indications of the effectiveness of the programme types evaluated.
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