The user may be prompted further if additional indications are needed to define the dosing region.
Long-term outcomes data on self-management from larger cohorts of people with different clinical indications are needed.
24 25 26 In addition to these safety studies using large databases, timely confirmatory prospective post-approval efficacy trials of the supplemental indications are needed.
For a successful purging strategy where a transgene is placed in close linkage with a gene or genomic block that causes a lower fitness in the wild habitat (Gressel 1999; Stewart et al. 2003), clear indications are needed of those negatively selected regions.
But you'd never much know it from "Legend," and if the idea is that the world of the Krays was some kind of bubble impervious to outside influence, some fuller indication is needed.
Although there may be multiple indications in a given patient, only one indication is needed to proceed with a biopsy.
As if another indication was needed.
If ever an indication were needed that the Anglo Saxon capitalist model were in trouble, a government bail out to the UK banking sector provides it in spades".
Therefore, while our findings, along with several others, suggest at least some reduction in ER-positive breast cancer associated with aspirin use, the evidence is not conclusive and additional prospective studies with detailed exposure data on the dose, frequency, duration, and indication are needed.
Although DNI in itself cannot be considered as an indication of NIV, the place of NIV as a ceiling therapy or a comfort treatment for patients with acute respiratory failure near the end of life is debated and a better delineation of the place for palliative NIV among overall indications of NIV is needed [19].
