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However, although nontherapeutic effect information of the types seen in the eligibility criteria is available for medicinal products as part of this authorisation information, it is not as organised and as accessible as the categorical characteristics or indications information nor is it standardised.
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The Primal congestion control is the source node dynamically adjusting the sending rate or window sizes depending on the indication information fed back from the Internet.
Compared with ANCC, FANCC requires the destination to broadcast 2m bits for the relay and transmission indication information, but the additional cost in the indication phase could be ignored if the length of broadcast-packet is large, which can be implemented easily and has great practical value.
The DrugBank database stores drug data with corresponding drug target and treatment indication information [38].
We used the indication information by 2009 from the drug labels from the Drugs@FDA database (http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Search_Drug_Name) to generate a list of drug-cancer associations (Dataset S1) that included 23 types of cancer.
DrugBank is a freely available online database that combines detailed drug data and indication information with comprehensive drug-target associations [ 18].
Most reports using medical records derive indication from the procedure report alone and in some cases the source of the indication information in the medical records was not clearly described [ 18, 33- 36].
Indication information is not considered a core component of the dosage instructions information but is assessed with them as provision of the reason for the medication can be given as part of the instructions.
Note that indication information in an eligibility criterion is subtly different from the combination of a particular diagnosis with a medication qualifier, although each describes a medication and a condition/symptom being treated.
Given the known lack of recording of indication information, the former pattern appears to be the more useful; yet the latter pattern appears to have more extensive use in eligibility criteria.
The former mainly involved one pharmacy, where local GPs were in the habit of specifying the indication in the directions (eg, 'One to be taken every morning for high blood pressure') but this indication information was omitted from the dispensed item (eg, the label would simply become 'One to be taken every morning').
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