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Since the OCB objective functions do not provide indications for estimating physical distances between markers and for comparing likelihoods of competing marker orders, only the three MLE objectives, namely, BASE TSP + MLE, Extended TSP + MLE, and Normalize TSP + MLE, were used in our computations.
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Although a global quantification of non-compliance is difficult due to its variations depending on the disease and also with regard to the different therapeutic indications, it is estimated to reach 50% for therapeutic indications in chronic diseases [ 13].
For instance questionnaires that include indication-for use and drug-specific questions increase prevalence estimates for drug use compared to open-ended questions [ 14].
Our objective was to describe indications for late preterm birth (LPTB) and estimate the frequency of potentially avoidable LPTB deliveries.
Similarly, Td coverage was not estimated because the indications for Td use (e.g. for use after tetanus-prone injury) were not known.
For a different subset of patients from the AMOS project (patients referred to AM therapies for any chronic indication), it was estimated that physicians enrolled every fourth eligible patient [ 18].
Finally, to test our assumption that utilization would be related to the indication for admission, mean estimates of utilization measures and rates of high intensity events were compared between admission indication categories.
We estimated the mean priority rating of all indications for each panellist and the median and the deviation from the panel mean.
Historical data reporting the number and indications for liver transplantations from 1988 to 2010 were used to estimate the number of transplantations attributable to chronic HCV infection.
42 Finally, to further assess the importance of the main indication for AD use, we estimated the aHR for ASD in children of mothers with a registry-based diagnosis of affective disorder compared with children of mothers with no such diagnosis, regardless of exposure to antidepressants.
Does this estimate cover all of the major indications for use of the product?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com