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The issues that arise in all potential indications are: a) how long it is reasonable to wait to prove insufficiency of response to monotherapy; b) by what criteria that response should be defined; c) how optimal is the dose of the first monotherapy and, therefore, how confident can one be that its lack of effect is due to a truly inadequate response?
Especially popular is the prospect of Crimea becoming part of Mother Russia - and all the indications are a majority wouldn't mind Russia sending tanks straight to Kiev.
Absolute indications are a RCC in an anatomically or functional single kidney, or bilateral RCCs.
In times of limited health care budgets, the availability of quantitative data on the medical need of a debilitating but not life-threatening condition, comparable across countries and indications, are a prerequisite for stakeholders and decision makers to engage into research and development of innovative treatment approaches.
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The potential use of erythropoiesis-stimulating agents (ESAs) for nonhematopoietic indications is a focus of current research.
The most common indications were a displaced proximal humeral fracture (54%) or osteoarthritis (30%).
Mr. Perez, by all indications, is an excellent choice.
However, antibiotic prescribing for urinary indications is an important exception.
Another indication is a patient with high and irregular heart rate.
One indication is a new pile of investors who have recently topped off Dedrone's Series A round.
In class, Scott Zigler always emphasizes that "indication" is a sign of bad acting.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com