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The appropriate use of analgesics for the self-treatment of these indications alone can explain the per-capita consumption of approx. 40 SU per year.
The demand for bone substitutes is more than 2.5 million units in this category of indications alone.
Subsequent to the timeframe we were studying, the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack (ALLHAT) trial showed increased major cardiovascular events in hypertensive patients treated with an A1B versus a diuretic, and we now know that the A1B medication class should be avoided for hypertension indications alone (ALLHAT 2002).
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Further studies are required before this indication alone could be retained in current practice.
For comparison purposes, we also fitted models using endoscopist indication alone as the outcome.
Our estimates when we excluded prevalent NSAID users remained the same, so it is unlikely that confounding by indication alone could drive the observed results.
It is difficult to apply this strategy for the range of conditions we have identified in our study – no indication other than cataract is of sufficient prevalence to justify a visiting specialist for that indication alone.
If the person entering data into the Obstetric Database did not check whether the test was actually performed, they may have falsely registered tests based on recorded indication alone.
Moreover, inter-institutional variation of overall CD rates was significantly correlated with the proportion of CDs performed electively in group 5 for this indication alone (Spearman's rho 0.86; P < 0.001).
In comparison, multivariate logistic regression using the endoscopist indication alone as the outcome provided an AUC of 0.791 955% CI: 0.765-0.816) for the full model and 0.761 955% CI: 0.734-0.788) for the best model selected by BIC.
The indication for AIT alone in phakic eyes consisted of IOP above target with progressive glaucoma on maximally tolerated medical or laser therapy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com