Exact(5)
Emphatically, Spencer-Brown (1969, Chap. 1) proposed such a procedure as the basis of all cognitive activity: "We take as given the idea of distinction and the idea of indication, and that we cannot make an indication without drawing a distinction".
11 Urinary retention was generally an acceptable indication without any qualifiers.
Sim et al. provides a very brief overview of a few studies of botulinum toxin for any indication, without providing much detail about key studies.
However, it would not be appropriate to establish a new indication without randomized controlled trial data to confirm these findings, similar to those recently conducted to study the antidiabetic properties of colesevelam (22).
In this sense, part of the extraordinary increase in AD prescription can be attributed to this group of patients, who previously failed to receive treatment for an indication without sufficient evidence of efficacy data available [ 15].
Similar(55)
"Companies could openly promote products for unapproved indications without testing these drugs," he said.
One study found that the use of these drugs for indications without federal approval more than doubled from 1995 to 2008.
Transfusion indications without specific motives were most likely to be made in sicker patients (APACHE II > 20).
Although the FDA approves more dangerous drugs for specified indications, without an indication there is no benefit to weigh against any nicotine risk.
At present, there are no other FDA-approved indications, and the manufacturer does not support or promote additional indications without the demonstrated efficacy studies and FDA-approved expanded labeling.
The mean heart rate of 73 ± 18 bpm is relatively high for CT coronary assessment because 79 of 82 CTAs (96%) were performed for other clinical indications without a specific heart rate reduction.
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