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Differences in patient characteristics according to PEG indication were assessed using Fisher exact test.
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The other licensed uses or alternative indications for these drugs were assessed using the BNF.
Protein concentrations were assessed using the Pierce ™ BCA Protein Assay Kit
Time trends were assessed using birth cohorts.
Potential interactions were assessed using logistic regression.
Differences between groups were assessed using ANOVA.
Fatigue was assessed using the Modified Fatigue Impact Scale (MFIS) and provides an indication of fatigue experienced by an individual in three domains; physical, cognitive, and psychosocial.
Dementia severity was assessed using the CDR.
Synchrony was assessed using SPIKE-distance58.
Subjective sleepiness was assessed using the Stanford Sleepiness Scale.
Depression was assessed using the MADRS [22].
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