The evaluation of bone quality should be performed in two species, such as the ovariectomised female rat model and larger animals (ewe, sow, primate etc).. Phase I studies are designed to enable determinations of pharmacokinetic profiles and bone diffusion and to offer indications of the putative clinical relevance of the dosages.
The first five BLAST hits served as an indication for the putative function of a contig.
The case studies described here, as well as other examples summarized in Table 1, demonstrate that the NMR screen provides a quick indication of whether the putative function assignment is likely to be correct.
Comparing the neuropsychological functioning between the BD I and BD II types of depression may provide indications of these putative different entities.
Although the evidence presented in this study is not strong enough to definitely reject Hypothesis 2, our findings provide a strong indication against the putative transfer of LI818 proteins during a cryptic green algal endosymbiosis event preceding red algal secondary endosymbiosis (Hypothesis 3), and favor a scenario with a transfer in the other direction (Hypothesis 4).
No less than the Oxford Dictionary has a definition for the term: "The putative ability of homosexuals to recognize one another intuitively or by means of very slight indications, " or, "the putative ability of heterosexuals to discern the homosexuality of others".
Thus, any identified association with antibiotics is at risk of confounding by indication (the putative cause and effect items are caused by a third event), for which adjustment is impossible owing to a lack of information.
The present data also provides an indication of a putative defect in GAG sulfation, which may lead to dramatic biological effects, as exemplified by mutations in PAPSS2, SLC26A2, gPAPP or SUMF1, all causing skeletal dysplasias [41] [44].
The importance of an input gene in the prediction of the target gene expression pattern is taken as an indication of a putative regulatory link.
