This situation gets more dramatic by expanding the spectrum of indications on the basis of dubious diagnoses with the aid of technical equipment such as kirlian photograpy.
The Shared Medicine Profile thus contains information about all prescribed medication and any medication provided by health care personnel along with information about the indication on the basis of which the medication is prescribed or provided.
One research physician abstracted and classified the CT indication on the basis of information from CT reports; examples include suspected pulmonary disease, cardiovascular disease, traumatic injury, or mediastinal disease.
Although meeting the regulatory criteria to approve biosimilar medication for a given indication on the basis of comparative studies with the reference product may be sufficient to support switching, substitution of insulins at the pharmacy level will require more substantial clinical data.
23 The FDA would also be permitted to approve such indications on the basis of only summaries of data in such circumstances, rather than being required to review the data in detail.
The drugs were chosen to cover a broad spectrum of mechanisms of action (including drugs sensitive to MDR mechanisms) to give an indication of the molecular basis of resistance in PC-3/TP201565 cells.
In our case, molecular dynamics simulation study revealed a consistent value of the energy of the molecule throughout the time period of simulation, which is an indication of strong basis of the fact that the molecule has a stable structure as required for the virtual screening and drug designing processes.
Indication extrapolation forms the basis of the biosimilar concept, and without it there would be minimal financial benefit associated with biosimilars [ 29].
To clarify these 'guidelines', albeit simplistically, refer to score indications that form the basis of an interpretation: e.g. that given sotto voce/pianissimo markings are not substituted for a preferred mezzo forte/forte, or broad largo/lento tempos exchanged for the faster pace of an Allegretto.
