There was a 105-fold fall in viable parasites with less than 100 viable parasites observed in the organs after PC-SA-SSG therapy, which is a clear indication of nearly complete healing.
We have reworded the manuscript to address the apparent discrepancy between the gel filtration and single-molecule assays for R378A, making it clear that the single-molecule assays are more sensitive in terms of detecting an interaction and that not seeing co-migration by gel filtration is not an indication of a complete abolishment of that interaction.
This is because late follow up is confirming the early indications of durable complete remissions that are long lasting with patients now regularly alive disease free for more than 10 years, albeit only 2 5% of the original cases.
The large overlap between the two completely different approaches is a strong indication of a virtually complete coverage at least of the most abundant I. ricinus midgut transcripts in unfed and partially fed stages as well as a complete overall transcript coverage of house-keeping transcripts.
That 20-0 lead was an indication of the Tigers' complete domination of the first half as the home side enjoyed 66% of possession in front of 11,837 fans.
In girls the interval from the first indication of puberty to complete maturity may vary from 18 months to 6 years.
The DHCPR aims to fill the conceptual framework with the most useful indicators of health care performance that give the most complete indication of real practice.
Because each subject has a different time course of responses, averaging difference curves may not provide a complete indication of group differences.
Although the FQI metric appears responsive to prescribed fire effects on plant communities in the Missouri Ozarks, the inclusion of species richness and mean CC provide more complete indication of plant community response than FQI alone.
A more complete indication of the treatment group difference can be seen in the cumulative distribution curves (supplementary Figs. A3 and A4, available in the online appendix).
