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The DNA damage-dependent phosphorylation of Chk1 has proven to be an adequate indication of checkpoint activation and is well-recognized in numerous model systems [37], [38].
(E ) Re-budding in the presence of nocodazole was taken as an independent indication of checkpoint deficiency.
Similar(58)
The activity of checkpoint blockade immunotherapy is not restricted to melanoma or lung cancer, and additional indications are expected in the future, with responses already reported in renal cancer, bladder cancer, and Hodgkin's lymphoma among many others.
His version of checkpoint guns are toys.
Proper functioning of the mitotic checkpoint requires the recruitment of checkpoint proteins to the kinetochore.
We propose that PP1Dis2-mediated dephosphorylation of checkpoint components forms a novel spindle checkpoint silencing mechanism.
1– 3 Although there have been recent encouraging therapeutic approaches using pathway and checkpoint blockade approaches and some indication of prolongation of survival, in many centers, the typical treatment options for disseminated disease still remain seriously limited in their ability to induce long-term survival.
The next checkpoint will likely be their announcement of retail or OEM deals, but there is no indication of when that will happen.
An indication of lax security?
But there's no indication of ownership.
"It is an indication of more conviction".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com