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In summary, there is some indication of benefit from temozolomide, but the evidence is too weak for firm conclusions to be drawn and further large RCTs are required.
Current use of multivitamins (a major source of retinol), and supplements of vitamins C and E were all unassociated with risk, and there was also no indication of benefit with longer duration of use.
At 56 and 90 days however, there was an indication of benefit from ATIII treatment for those patients who were alive and still in hospital for that length of time.
We tackled this issue for women aged 40-49 in an earlier report 7 and found that after adjusting for use of mammography in the community in the control group, largely for diagnosis, there was still no indication of benefit from the mammography screening in the intervention group.
In the four of the seven patients who had had drug changes with a shorter period of follow-up, some early indication of benefit for some seizure types at least was apparent in three (the one patient with no or minor change in seizure frequency had stopped carbamazepine, but not yet started any new anti-epileptic drug).
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Having shown the possibility of simple implementation and indications of benefit, this motivates further exploration of these directives and their implementation in hardware, as well as their support by programming tools.
There were clear indications of benefit to those involved in the process, although wider benefits were difficult to demonstrate at this stage.
Overall, a consideration of outcome measures, alongside refined methodology as discussed earlier, would allow researchers to assess whether the preliminary indications of benefit seen here can be replicated.
While few studies reported consistent and statistically significant evidence of impact on perinatal mortality associated with the intrapartum interventions we reviewed, several interventions show promising indications of benefit for specific indications or in certain settings.
Since clinical trials specifically in RPGN are unlikely, use of biologic registries or combination of sufficient sized cohort series may provide indications of benefit outside of a clinical trial setting and should be encouraged, in order to provide some evidence for the efficacy of therapeutic regimens in RPGN and advanced renal disease.
This is not to say that physical activity interventions need to await further scientific study there are strong indications of benefits in terms of well-being and quality of life, and in terms of physical benefits such as improved balance (preventing falls), and grip strength (supporting independence in ADLs).
More suggestions(16)
evidence of benefit
hint of benefit
proof of benefit
indicative of benefit
reflection of benefit
signs of benefit
indication of suicidal
indication of wrongdoing
indication of selling
indication of terrorism
indication of concern
indication of normalisation
indication of patience
indication of ownership
indication of collaboration
indication of contrition
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