We considered documents as relevant to off-label drug use, if they referred to any human drug outside the approval purposes, in terms of different dose, indication, route of application or for another age group.
It is noteworthy that both ministerial programs mention the study of evolution without any indication of its application to the evolution of the human species.
The inhibition of lipid peroxidation potential of PTVO (Table 2) could be a positive indication of its application in food processing and preservation.
The mitochondrial activity assay provided good evidences of cells viability on the Gel/MMT CS membranes, giving an indication of possible application as a matrix for tissue engineering.
From these comparisons, e.g. for nicotine uptake levels, no indication of sugar application-related differences could be derived.
Quantitative and qualitative parameters gave good indications of potential application of the technique to diagnosis and follow up of patients submitted to CRT.
Early indications of the application of this technology in lung cancer are that PET/CT confers statistically significant improvements in accuracy over PET and CT alone [ 10, 11].
"There were indications that application of power of command, expert knowledge, and position were employed in a manner to suggest possible coercion," the report concluded.
From this law, another ten are deduced whose titles provide a useful indication of their possible application.
The opinion noted that "when a statute gives no clear indication of an extraterritorial application, it has none".
These three approaches are briefly discussed and some indication of their potential application to cancer risk assessment is outlined.
