We found an indication for this application in the course of our experiments on a sample of methyl linolenate.
The radiobiology of radiosurgery in particular for the central nervous system plays a crucial role for the clinical indication and the application of a therapeutic radiation dose in single session.
We defined an orphan drug as one designated as such in FDA's online orphan drug product designation database 16 for the proposed indication in the application.
In order to provide general indications for clinical application, the group analysed the data from the New York Stony Brook University Hospital trauma register [19].
However, sometimes side effects occur such as ileus, fever, leukocytopenia and so on, so that it has been necessary to determine the indication for this therapeutic application to avoid such side effects.
Further controlled clinical studies are needed to show if iloprost has any effects on joint cartilage and to investigate if osteoarthritis-related BME is an indication for future application of PGI2 and related molecules.
This paper contains a methodology for the design and manufacture of implants in cases when the medical indications favour the application of an anatomic custom design implant.
Secondary outcomes were the main indications for acute application of NIV, the predictors of NIV failure, ICU and hospital lengths of stay, in-hospital and mortality at day 28 and the main complications associated with noninvasive ventilation.
Up to date, approvals for the application of several photosensitizers against malignant and nonmalignant indications exist in Europe, the US, Canada, and Japan [ 4].
Since the surgical technique is simpler and the indications for application are wider, the Dynawrist fixator seems to be a good alternative to the Hoffman II fixator.
