Indications for changes in the treatment regimen included persistent fever ⩾72 h, positive culture results with resistant organisms, or clinical deterioration at the discretion of the treating clinician.
A good indication for such changes is the correlation of the intensities between D and G bands (Fig. 3d, f).
Fibrosis fraction: The degree of fibrosis, or collagen content, was quantified to give an indication of changes for overall collagen content within the parenchymal tissue using a previously described method [ 6 ].
Furthermore, we recorded any change of endocrine agents and the indication for the change: sequential therapy (switching after 2 3 years of adjuvant tamoxifen therapy to an aromatase inhibitor), extended therapy beyond 5 years of adjuvant therapy or change due to adverse effects.
Nevertheless, identification of a particular protein as reporter-TF is a strong indication for the change in its activity following SDH3 deletion.
A patient was considered in clinical DAS44 remission if he/she reached a DAS value of <1.6 11 for at least two consecutive visits 3 months apart, and if they also had no disease flare within the previous 6 months, stable treatment for 6 months and no clinical indication for a change of treatment.
However, the similarity in neonatal jaundice (and stool production) observed in the present study provide an indication for a "change in paradigm" with respect to the effect of breast feeding on the exaggeration of neonatal jaundice during the first postnatal days.
However, indications for behavioural changes were observed at the population level, even though these data do not allow a causal link to Allez Hop.
There are no studies available that estimate the sensitivity and representativeness of the system, but there are no indications for systematic changes in notification in recent years.
