A patient was considered in clinical DAS44 remission if he/she reached a DAS value of <1.6 11 for at least two consecutive visits 3 months apart, and if they also had no disease flare within the previous 6 months, stable treatment for 6 months and no clinical indication for a change of treatment.
However, the similarity in neonatal jaundice (and stool production) observed in the present study provide an indication for a "change in paradigm" with respect to the effect of breast feeding on the exaggeration of neonatal jaundice during the first postnatal days.
In all strains of clade LB, on the other hand, indications for a change of codon usage were found, although to different extent.
The changes in distribution of tumor localization might be an indication for a true change in disease.
Indications for such a change are: secondary infection, such as Bacillus coli or other penicillin-resistant organisms, or interference with the flow of penicillin through the septic area.
When requested for OR indication, a change in treatment (Tx change) is defined as a good outcome.
Although we have no information about the indication for the medication of each individual, it is reasonable to assume that the indication for a prescription does not change when the (antihypertensive) drug for the individual patient changes.
Nevertheless, identification of a particular protein as reporter-TF is a strong indication for the change in its activity following SDH3 deletion.
Of those allocated to expectant management, 20/32 (63%) women had intervention before spontaneous onset of labour (or planned delivery if elective caesarean was indicated) for one or more indications, including a change in maternal or fetal condition requiring delivery (7/20, 35%), maternal request (10/20, 50%), and obstetrician decision (14/20, 70%).
This further indication for a need for conformational changes within the receptor complexes also underscores the importance of comparisons with the evolutionary related IR/IGF1R system in which the covalent nature of the receptor dimers clearly necessitates additional allosteric control mechanisms.
"I view this as an indication for collaboration and change, rather than in a negative light".
