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The wide variation in percentages of DAD in patients with ARDS (from 13.5 % to 57.84 %) based on open lung biopsy may be attributable to the different indications, definition and timing for open lung biopsy in each of the studies.
The ADDDK and DADDDK are established by the dosage for the main indication (following the definition of the DDDA by the ESVAC and the DDD by the WHO) for which the AVMP or active compound is authorized.
There is no indication that the definition should be different in pregnancy, and in other pregnancy studies the same cut-offs for deficiency and insufficiency have been used as for non pregnant adults [ 28].
Given this definition, indications are provided for choosing the most robust sensor configuration or how to improve the robustness of any one of the sensor configurations.
There are a number of limitations to this study, which stem partly from the sensitivity of the subject and its relatively small scope, and partly from the methodological challenges of studying a phenomenon which is associated with such intense debate about its definition, indications and practice.
Some caution has to be exercised in interpretation of the literature as there are differences in terminology with respect to both palliative care patients (some corticosteroid studies relate only to 'advanced cancer' or 'pre-terminal' cancer) and to the categorisation of corticosteroid indications, particularly the definition of 'non-specific' symptoms.
There are 1772 text annotations on classes and 4711 on labels, e.g., alternative definitions, indications of synonymy, indications of candidacy for external ontologies, tags facilitating internal workflow management, and personal annotations.
In other markets, the insurers are requiring a credit score of at least 680 — an indication of how the definition of a good credit score has changed as the economy has deteriorated.
Future research should include description of the definition, treatment indication, and objective outcomes.
In our study, not all patients who had an indication according to our definition received prophylaxis.
A GAS score of 50 is, by definition, an indication of overall goal attainment at the expected level.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com