For the present drugs identified as eligible for analysis, information regarding approved indications, characteristics of the products, and clinical trial data were extracted from review reports downloaded from the website (http://www.info.pmda.go.jp) of the regulatory authority (Pharmaceutical and Medical Devices Agency, PMDA).
Therefore, this retrospective study aims to compare recorded data on two types of LH, i.e., LAVH and TLH, with respect to indication, operative characteristics, and adverse outcomes.
The dominant innovation design (e.g. techniques or resources used) which diffuses or its application fields (e.g. indication, patient characteristics) differ from those assumed in impact assessments and side-effects which occur in other markets.
13– 16 In comparison, the WDHR-CCTR is a semi-national, multicenter registry with detailed information on indication, patient characteristics, procedural data, CT outcome, and clinical consequence.
We also studied age-stratified utilization rates, indications, and characteristics of patients undergoing these procedures.
Moreover, extensive physicochemical characterization of the PAC in terms of, but not limited to Fourier Transform Infra-red (FTIR) spectroscopy, Scanning Electron Microscopy (SEM), particle size and distribution analysis were carried out, and there were indications of characteristic improvements when compared to our previous investigation.
Although we cannot rule out clinically relevant inconsistency (the upper credible interval for the inconsistency factor crossed the pre-specified threshold for a clinically relevant effect at 0.9 cm), we have no indication that clinical characteristics of included patients or other trial characteristics confounded the indirect comparisons.
This foundational framework will be elaborated for multiple contexts with an indication of desirable characteristics specific to representative situations.
TDS is not associated with health effects but it is an indication of esthetic characteristics of drinking water.
