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Physiological mode of action predictions from DEBtox can provide a useful indication of the basis of the toxic effect.
The Shared Medicine Profile thus contains information about all prescribed medication and any medication provided by health care personnel along with information about the indication on the basis of which the medication is prescribed or provided.
One research physician abstracted and classified the CT indication on the basis of information from CT reports; examples include suspected pulmonary disease, cardiovascular disease, traumatic injury, or mediastinal disease.
The evidence summarised in this review provides some indication of the basis for practice but one must remember that there are weaknesses in some of the data that may make the results unreliable.
Although meeting the regulatory criteria to approve biosimilar medication for a given indication on the basis of comparative studies with the reference product may be sufficient to support switching, substitution of insulins at the pharmacy level will require more substantial clinical data.
In our case, molecular dynamics simulation study revealed a consistent value of the energy of the molecule throughout the time period of simulation, which is an indication of strong basis of the fact that the molecule has a stable structure as required for the virtual screening and drug designing processes.
The rationale, indications, contraindications, anatomical basis, and technique of scaphoid preparation, bone graft harvest, insetting, fixation, and microvascular anastomosis are presented for the treatment of scaphoid nonunions with avascular necrosis and carpal collapse.
This situation gets more dramatic by expanding the spectrum of indications on the basis of dubious diagnoses with the aid of technical equipment such as kirlian photograpy.
23 The FDA would also be permitted to approve such indications on the basis of only summaries of data in such circumstances, rather than being required to review the data in detail.
