Sentence examples for indicating that the modification from inspiring English sources

Additionally, in vivo studies demonstrate that dosing rats with the neurotoxicants 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine or 6-hydroxydopamine results in elevated levels of Cys-106 oxidized DJ-1 in RBCs32, indicating that the modification in blood DJ-1 may not only be a surrogate maker, but also be biologically relevant to PD.

By the ultra-sensitive differential scanning calorimeter (VP-DSC), it was found that the main denaturational transition temperature (Tm2) of modified collagen increased, while its calorimetric enthalpy changes (ΔH2) decreased compared to those of native collagen, further indicating that the modification of γ-PGA-NHS influenced the aggregation of collagen molecules.

The impact of LPNs on the hyaluronic acid distribution in rat cochlea did not cause either permeability change or hearing loss, indicating that the modification is unharmful.

Expression of this construct rescued a bah-1 mutation, indicating that the modification did not disrupt function.

We found that a t1-m6A target RNA had an affinity similar to that of equivalent non-t1-A targets (see updated Figure 3D and Table 2), indicating that the modification effectively blocks t1-A recognition.

Extracts obtained at specific stages, i.e. the early ring stages, mature trophozoite and schizont stages, revealed differential pattern (data not shown), indicating that the modification targets stage-specific proteins or modifies the same protein differentially in a stage-specific manner.

We can see that for RNase R there are no changes at the protein level, indicating that the modifications observed for PNPase are specific.

Study by Chen et al. [ 37] has shown that the N-terminus of the CP of PPV is modified with O-linked N-acetyl glucosamine in N. clevelandii, N. benthamiana and Arabidopsis, indicating that the modifications are not host specific.

This enhanced generation of both chain types was not visible when Nedd4-2 or AIP4 instead of Nedd4 were overexpressed (results not shown), indicating that the modifications of Beclin 1 are catalysed by Nedd4.

Each Skp1 isoform was capable of high-affinity binding to a natively soluble F-box protein, Fbs1, based on pull-down studies, indicating that the modifications are not required for FBP interaction as previously shown for FbxA.

This result indicates that the modification is quite effective.