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Importantly, patients who manifested ARC on day 1 were significantly more likely to do so on subsequent measures, indicating that augmented drug CL is unlikely to be short-lived.
Interestingly, this NF2 KO phenotype was completely prevented in mice that were also haplo-deficient for Yap, indicating that augmented Yap activity is responsible for this pathology [99].
Lower PPTs were associated with high VAS-GH and TJC, but not with ESR or SJC, indicating that augmented pain processing may be associated with inflated DAS28 in people with well-controlled inflammatory disease.
Selected genes had the additional characteristic that their 5'-UTR ribosome occupancy rates were positively correlated with their translation efficiencies, indicating that augmented protein production is a consequence of increased ribosome occupancy.
As CXCR3 is predominantly expressed on memory T cells, subpopulation analysis revealed increased percentage of peripheral CXCR3+ CD8 but no CD4 TEM cells in acute RSV infection, indicating that augmented antiviral type-1 CTL response is necessary to balance type-2 microenviroment and restrain viral infection [ 34].
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These data indicate that augmented NRP2 expression is caused by canonical TGF-β/Smad signaling.
These data strongly indicate that augmented spinal expression of neuroligin 1 in Eif4ebp1-/ mice contributes to mechanical hypersensitivity via neuroligin 1-induced upregulation of excitatory synaptic transmission in the spinal cord.
Fungus-induced mortality rates were significantly higher in the fungus and insecticide co-exposure treatments (F+P) (Figure 4), indicating that permethrin augmented the proliferation of B. bassiana and M. anisopliae in both the laboratory colony and field-collected mosquitoes.
Id2 and Id3 ectopically enhanced reporter activity indicating that it augments Notch signaling.
Human articular chondrocytes synthesize and constitutively release sPLA2, and are therefore suggested to be responsible for the high concentration of sPLA2 present in articular cartilage [ 32]. cPLA2 is also reported to be involved in PGE2 production by osteoblast cells [ 33], while there are reports indicating that sPLA2 augments cPLA2 expression in mouse osteoblasts via endogenous PGE [ 13, 34].
Results indicate that friction factor reduces with augment of open area ratio, pitch ratio and Reynolds number.
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