Sentence examples for indicating mechanisms from inspiring English sources

Cell based therapy requires extensive preclinical characterisation of biomarkers indicating mechanisms of action crucial to the desired therapeutic effect.

However, these constitute only ~50-70 ~50-70FR-TKI resistant cases, indicating mechanisms leading to resistance in the remaining cases are yet to be unraveled.

In T-ALL cell lines, there was significant IC50 correlation between DNR, DOX, VCR and ARA-C, consistent with previous studies indicating mechanisms of cross-resistance for these drugs (Kaspers et al, 1998; Martin-Aragon et al, 2000; Lofgren et al, 2004).

Together, these data indicate mechanisms of the stress response and redox signaling involved in VSMC cell death induced by proteasome inhibitors, which may be of relevance to understand the therapeutic potential of such compounds in vascular diseases.

Cell cycle effects of XR5944 also indicate mechanisms of action that are distinct from that of known topoisomerase inhibitors.

Secondly, the serum lactate level reflected the difference between lactate production and elimination; thus, an increased lactate level may also indicate mechanisms other than cellular hypoxia or hypoperfusion.

Comparison of E2 uterine transcript profiles and those of other estrogenic chemicals of interest in vivo indicates mechanisms and activities of test compounds.

As suggested above, they rather indicate mechanisms acting preferentially in specific duplicated regions, and most notably in the duplication between chromosomes 11 and 12.

This finding, along with the diverse anti-apoptotic or growth promoting pathways activated or modulated by TIMP-1 indicates mechanisms not classically mediated through MMPs.

By measuring crosstalk between subsystems it can also indicate mechanisms by which such systems may be controlled in experiments and therapeutics.

One way of indicating causal mechanisms in relation to offender purposes is to identify crime scripts.