Sentence examples for indicating dose from inspiring English sources

The use of CoV as a metric may be advantageous, as it was recently indicated that although measures such as D70 can be useful in indicating dose heterogeneity, the slope of the DVH also appears to be important [10].

Higher activity was observed with increasing concentrations of test extracts indicating dose dependent response.

Lower concentrations of BAY 80-6946 (10 or 50 nM) showed similar, albeit less pronounced shifts in the same direction indicating dose dependency.

Mean (±standard deviation) values for peak concentrations were 351 (±226), 595 (±400), and 1195 (±700) pg/mL, respectively, indicating dose proportionality.

The dose-normalized plasma exposure following i.v. dosing at 20 mg/kg resulted in a similar value as with 30 mg/kg (0.28 versus 0.24 hours* μmol/L), indicating dose linearity within this dose range (data not shown).

Results of the statistical analysis for the oral dispersion gave values for β (95% CI) of 0.89 (0.47, 1.32) and 0.56 (0.83, 0.83) for AUC 0,∞) and Cmax, respectively, indicating dose proportionality for AUC 0,∞) but not for Cmax.

Within the dose range of 1 to 450 mg, tissue-to-blood AUC ratios decreased from 10.6 to 0.75 ± 0.16 for the spleen, 7.5 to 0.86 ± 0.18 for the liver, 3.6 to 0.48 ± 0.13 for the bone marrow, 0.69 to 0.26 ± 0.1 for the lung and 1.29 to 0.56 ± 0.14 for the kidney, indicating dose-dependent uptake.

The 95 % CI for both variables included 1, indicating dose-proportional PK of selexipag in the dose range tested.

Additionally, recent studies in breast cancer have indicated dose capping may result in underdosing of some patients[24], [25].

Recent real-world studies indicate dose similarities between DET and GLAR [ 19- 21].

Pharmacokinetic studies of the prodrug and the active metabolite indicated dose proportionality.