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Two days after transfection, we scored cells containing two or more distinct nuclei indicating defective mitosis (Figure 6).
These protein aggregates exhibit features indicating defective degradation of misfolded proteins.
Deficient caspase activation despite released cc results in negative CRAC values indicating defective apoptosis signaling.
In the VH, 68% of GRP78-positive cells were also positive for p62 indicating defective autophagy flux.
Sisters remained apart (100%), and chromosome fragments were evident, indicating defective repair of DSBs by homologous recombination.
At baseline, a subcohort of T2DM HT and HT alone participants showed evidence of nitric oxide synthase (NOS derived superoxide production, indicating defective enzymatic activity.
Similar(43)
Despite the lack of a hexamerisation defect in crosslinking experiments, this effect could indicate defective intermolecular interactions that can be overcome once the hexamer is formed.
In this situation, the appearance of pneumococcal sepsis indicates defective protection against pneumococcal invasion.
The decrease in BrdU uptake in NFAT5−/− cells indicated defective DNA replication, which was in agreement with results by Go et al. showing reduced 3H-Thy incorporation in NFAT5-deficient lymphocytes under osmotic stress [24].
A distance of >1.5 microns indicates defective SCC.
Increased mitotic index in the presence of colcemid indicates defective COC.
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