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By day 7, the number of the ΔrelA ΔspoT mutant began to decline in all tissues, indicating clearance by the host, while all of the mice inoculated with wild-type Y.
Of note, various PDE5 inhibitors selectively increased the apoptotic index in TGF β1-induced Peyronie's disease-like plaques in rats [ 117, 118], indicating clearance of myofibroblasts by apoptosis upon enhancement of NO signaling.
These antibody responses were defined as GMTs in women in the TVC who were DNA-negative but seropositive at Month 0 for the antigen under analysis, indicating clearance of natural infection.
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Our data here indicated clearance rate less than in previously documented experiments for some ciliates (Dolan 1991; Simek et al. 1995). in which lower bacterial densities were used.
Followup samples obtained 3 months later for each patient indicated clearance of WU virus.
Blocking ASGP-R by injection of asialofetuin prior to injection of IgA1 or IgA2 EGFR inhibited clearance of IgA EGFR from the serum in the first hours, indicating that clearance by glycoprotein receptors, such as ASGP-R, contributes to the short serum half-life of human IgA EGFR in mice (Fig 2).
Bacterial clearance was observed regardless of whether the worms were fed with live or dead (gamma irradiated) E. coli, indicating bacterial clearance was due to the consumption of bacteria by worms rather than the death or lysis of bacteria.
No virus was detected in any sample from day 14, indicating viral clearance.
We observe that the ability of monomers and dimers to reach the blood stream is not limiting, and that their levels spike at different times, and also fall quickly indicating rapid clearance (Figure 3).
Overall, bacterial numbers in lung and spleen decreased over time, indicating partial clearance.
From 10 to 11 wpi, levels were significantly reduced, indicating a clearance of virus.
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