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A variety of genetic alterations of podocyte proteins indirectly lead to an aberrant cytoskeletal structure, indicating a sensitive signaling balance that can be influenced by mechanical as well as cytokine based signals [6] [9].
Bathe et al. [ 74] showed that the bending stiffness κ b is state-dependent and derives from a generic interplay between the high stiffness of individual filaments and their rather soft sliding motion, indicating a sensitive dependency on time and length scales for responses against external influences [ 75, 76].
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The 2.7-fold (p ⩽ 0.05) increased transcription of heme oxygenase-1 indicated a sensitive antioxidant and stress response, while cell viability did not reveal a toxic mechanism.
A resistant mutant has a positive interaction score, whereas a negative score indicates a sensitive mutant.
No growth in the LJ medium with anti-tuberculosis drugs indicated a sensitive strain.
This may indicate a sensitive period of gestation in relation to PM10 exposure, but it may also be attributed to the strong correlation in ultrasound measurements.
The presence of distinct embryonic lethal phenotypes in homozygous and LVOT phenotypes in heterozygous Matr3Gt-ex13 mice indicates a sensitive dependence on Matr3 gene dosage for different developmental processes.
The predeliction for DBP-induced loss of OCT3/4pos germ cells may indicate a sensitive stage of differentiation rather than gestational age, and this requires further clarification; specifically, there may be more marked effects in earlier gestation when more of the germ cells are undifferentiated.
Although the overall abundance of p53 was greater under permissive conditions, the degree of change between DMSO and etoposide treatment was much greater under non-permissive conditions indicating a more sensitive detection of DNA damage under non-permissive conditions mediated by p53.
Conversely, the Overall Problem measure reflected clinical change only after a gain of over 11 points, indicating a less sensitive scale.
At the acquisition time of 2 min, the required volume of sample was approximately 2 pmol, a value indicating a highly sensitive analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com