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At the AKAP gene, WT cells exhibited half-lives ranging from 5.8 hours to 19.8 hours at the various exons (Suppl. Fig. S6A - blue hatched line and Suppl. Table S1) while PARP1 depleted (KD) cells exhibited half-lives ranging from 1.6 hours to 3.9 hours, indicating a dramatic decrease in stability in the PARP1 depleted state (Suppl. Fig. S6A - red hatched line and Suppl. Table S1).
In 1978 the geometric mean B-Pb level was 60 μg/l, whereas in 2007 it was only 13 μg/l, indicating a dramatic decrease in B-Pb during the period 1978 1994 [ 4].
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Results of the ferroxyl tests indicated a dramatic decrease of corrosion sites by superimposing −1000 V on DC bias.
By generation 9, the number of polymorphic makers had decreased to 12% (TM) and 8% (IM), indicating a dramatic loss of genetic diversity.
In contrast, overexpression of KLF17 induced the cell cycle resting phase GO/G1, decreased S and G2/M phases to reduce DNA synthesis, indicating a dramatic impact on cell cycle progression.
The H2RG, with a unique configuration designed to decrease the capacitive coupling between ROIC pixels, had an IPC of 1.8±1.0% indicating a dramatic improvement in IPC with no measurable asymmetry.
However, analysis of maternal milk from Ukraine, donated 1993 1994, showed a median p,p'-DDE concentration of 2457 ng/g lipid [ 11], which is considerably higher than the median lipid adjusted p,p'-DDE concentration in serum of 650 ng/g lipid in the present study, indicating a rather dramatic decrease in exposure during the last decade.
Evaluations of myelin thickness and axonal diameter (AD) using design-based, unbiased stereology revealed alterations in myelin structure that indicate remyelination, specifically a dramatic decrease in the average internodal length (IL) and an increase in the proportion of axons with thin myelin sheaths.
The development of the NRR does not indicate evidence for a dramatic decrease in the benefit levels across EU-15 countries.
Carrier screening, followed by prenatal diagnosis when indicated, has resulted in a dramatic decrease in the incidence of Tay-Sachs disease in the Jewish population.
QRT-PCR confirmation indicated a dramatic 57.4 fold decrease in preprohypocretin transcript abundance, identifying the known central feature of narcolepsy.
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