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Strains defective in Suv3 or Dss1 show accumulation of mitochondrial mRNAs, indicating a defect in their turnover (Dziembowski et al. 2003; Malecki et al. 2008).
In addition, one dark spot marked by a square only exists in the middle subcell, indicating a defect located in the GaInAs subcell.
Moreover, the tight junction protein ZO-1 is mislocalized in the tal1-deficient endocardium, indicating a defect in intercellular junction formation.
The resulting virus particles have a regular protein composition and no changes in their morphology were obvious by electron microscopy, but their hemolytic activity is reduced indicating a defect in membrane fusion.
Despite the increase in mRNA levels, HAD-Tg mice show no significant increase in the level of DAT protein in the striatum, indicating a defect in protein trafficking or stability.
With PFOA exposure, cytosolic PKC concentrations were significantly elevated for all three isoforms; despite the overall increase in PKC expression, membrane-associated PKC was unaffected, indicating a defect in PKC translocation.
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The D peak is negligible in all the cases, indicating a defect-free graphene growth.
The doped SWCNTs often show radial breathing mode peaks in the off-resonance region, indicating a defect-induced modification of absorption spectrum.
Results show a reduction of approximately 50% in both mutant strains and clearly indicate a defect in nuclear oscillations, most probably linked to defective cMT functions.
These results indicate a defect in the migration of renal embryonic endothelial cells that may cause defective glomerulogenesis (Fig. 3A).
She didn't wholly escape the criticism that comes with a New York primary, however, as conflict erupted over whether the multiple Metrocard swipes she needed to get onto the subway indicated a defect in her character or the card's.
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