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Normal epidermis was predominantly negative for p53, as p53 is rapidly degraded in undamaged cells, but occasional p53-positive cells were seen (1 3%), indicating a damage response.
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Further results obtained from centrifugal tests indicated a damage mechanism related to impact from olive seed particles.
Increased urine beta2-microglobulin value indicates a damage of renal tubules because of the decrease of reabsorption.
Thick, billowy smoke may indicate a damaged muffler.
In other cases TEWL values slightly increase indicating a reduced damage.
FeSO4 and H2O2 treatment individually showed two bands but the lower band was more concentrated, indicating a minor damage of DNA.
We were also able to detect the repair pathway sensor kinase ATM at induced γH2AFX foci in fibroblasts indicating a DNA damage response pathway operates in platypus (Additional file 1: Figure S1).
In addition, it has been demonstrated that podocytes exposed to IFN- γ and IL-4 also altered vimentin and laminin expression; indeed both of them interfered with monolayer integrity when added to the basolateral side of podocytes, indicating a selective damage [ 52].
Even though the WTC approach did not yield higher damage costs as expected, the estimates are about the same magnitude, indicating an economic damage cost of about 200 US$/household from the 2007 floods.
Furthermore, enhanced P-CTD cleavage was observed in both yeast and human breast cells following UV-irradiation indicating a conserved eukaryotic damage response.
In contrast to hard signs, the presence of neurological soft signs has been thought to indicate a diffuse damage of the brain, not related to damage of a specific brain region.
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CEO of Professional Science Editing for Scientists @ prosciediting.com