In fact, almost 30% of the sample indicated being unable to perform usual tasks.
However, this presence was due to the fact that we did not consider this stage as a contraindication to TACE, if the shift from B to C stage was only caused by PS-1 which, in the ECOG definition, indicated patients ' unable to carry out a strenuous exercise but able to perform the usual activities of normal life'.
Indeed, when a more restrictive 7-AAD gate was set, the cluster in the bottom left corner was no longer present (Fig. 2B), and this finding was confirmed by in vitro functional data that indicated HSCs unable to form colonies had higher levels of 7-AAD at the time of sorting.
He also said satellite images showed that Mr. Assad was directing artillery at highly populated regions and acting "extremely brutally, which displays their desperation and indicates they are unable to find more efficient solutions to pacify the uprisings".
Roddick was two sets to love and 4-1 ahead when Davydenko indicated he was unable to continue in the stifling heat in Melbourne.
Consistent with confocal microscopy data (Fig. 8F, 8G, and 8J), EM analysis revealed no significant effects of Trak1 WT or Trak1 hyrt expression on mitochondrial length (Fig. 9C) or mitochondrial size (Fig. 9D) in MFN −/− MEFs, indicating Trak1 is unable to promote mitochondrial fusion in the absence of mitofusins.
These results indicate that, although unable to induce ERK1/2 phosphorylation in resting cells, TRAF4 potentiates the ERK1/2 signaling pathway in proliferating HeLa cells.
The test is terminated when participants indicate they are unable to continue the protocol, or when their vital signs warranted.
Fifteen family carers agreed to attend the focus groups or interviews, four indicated they were unable to attend due to family and work commitments.
Although many participants had contacted their local arthritis consumer organisation, some indicated they were unable to obtain the information they were seeking.
