Zebrafish Vhl shares 52% amino acid identity with human VHL, and knockout studies indicate that it is functional in the hypoxic response (van Rooijen et al., 2010).
In other words, the evidence for expression of miR437 in grass species beyond rice is presently unclear: the presence of a conserved sequence would indicate that it is functional.
Injected Texas Red Dextran labeled the 10.1.1 Ab-positive lymphatic vessel, indicating that it is functional in draining lymph from the tail past the tumor and through the ING LN to travel through the efferent SE lymphatic vessels.
The conservation of this domain indicates that it is a new functional gene and suggests that it has retained a MFS function.
A predicted protein complex with low p-values indicates that it is enriched by proteins from the same functional group and thus statistically significant.
Our evidence indicates that it is critically important to better understand the functional roles of MD (as well as other adjacent thalamic nuclei) in the development of the PFC, in order to understand how the cortex is involved in cognition.
Moreover, the co-expression of genes suggests that genes in a gene signature are often interchangeable as illustrated in a reanalysis of the van't Veer et al. [12] data set [39], indicating that it is the functional processes captured by a gene signature and not the individual genes that is of importance [22].
When expressed in HEK293 cells, GST-hDyn partially localized to the spindle, indicating that it is a functional MT-binding protein.
We also demonstrated that PdGAUT12.1, which is highly expressed in developing xylem, can complement the phenotype of Arabidopsis irx8 mutants, indicating that it is a functional homolog of the Arabidopsis GAUT12.
The Little Skate SINE fragment lacks the 5' promoter for transcription by RNA III polymerase, indicating that it is a non-functional retroposon although it may have accumulated some other function which accounts for the degree of sequence conservation to SacSINE1.
Olender et al. [ 2] demonstrate that 57 human ORs show evidence of strong purifying selection - that is, selection against non-functional variants - indicating that it is an adaptive advantage to have a functional variant of these ORs.
