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In the CALR-compromised sub-network, a high betweenness score indicates load and importance of Pitx2 to the sub-network, while high radiality demonstrates functional relevance and control that Pitx2 exerts on neighboring nodes [ 24, 35].
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Figure 9 indicates loads of all specimens at initial cracking, yield and ultimate.
As is shown in the figure, the third step in the process involves solving a mixed integer nonlinear programming problem due to the existence of nonlinear power flow constraints and binary variables indicating load transfer.
Although the data indicate LOAD therapy is statistically superior to the standard of care, this study has several limitations.
Arrows indicate loads, arrowheads indicate restricted nods, and spiral lines indicate springs.
To show the deformation features, the volumetric strains are plotted at each of the indicated loading times.
This may indicate loading of newly-synthesized MHC-I molecules through the classical pathway and subsequent transport to endosomes, or alternatively may represent loading of nascent Kb molecules within ELCs.
Band intensity was normalised to the indicated loading control, and averages taken of three mice per genotype.
Cargo loading was also tunable by varying the number of layers deposited, with UV/vis spectroscopy and fluorimetry indicating loading of ∼44 μg of SIIN*/mg of particles and ∼67 μg of polyIC/mg of particles during assembly of (SIIN*/polyIC 3.
Bolded text indicates significant loading or cross-loading.
This factor indicates the load of the cell.
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