In unresuscitated or inadequately resuscitated septic shock, Rdes and Rres are decreased, indicating disturbed tissue oxygen metabolism and microvascular reserve.
Along with a large number of studies indicating disturbed iron homeostasis in obesity, recent data indicate a cause effect relationship between iron status and obesity-related pathologies.
We used Linear Discriminant Effect Size (LEfSe) analysis to identify fungal genera that consistently indicate disturbed or undisturbed (control) treatments across 5- and 12-month sampling times.
Overall the alterations in the metabolome detected in this study as associated with PCa bone metastases indicated disturbed molecular and cellular functions of clear relevance for cancer progression.
These findings may indicate disturbed fat metabolism in cancer patients.
A few studies in bipolar disorder also indicate disturbed interaction in this population [ 67– 67].
These findings indicate disturbed mother-infant interaction in depression [ 9, 66].
Most variants showed an increased susceptibility against proteolytic attack indicating disturbed folding kinetics (i.e. shift of the folding equilibrium towards the unfolded state) and local unfolding.
Also, the reported alteration in parvalbumin staining in hippocampal area CA1 of DISC1tr mice (Shen et al., 2008) may indicate disturbed GABAB-mediated inhibition and thus a loss of TA LTP (Remondes & Schuman, 2003).
Disturbed sleep due to hyperglycaemia was reported by 28 patients with type 1 diabetes: 24 patients indicated disturbed sleep less than once per week, two patients one to two times per week, and two patients reported a disturbed sleep by hyperglycaemia more than three times per week.
