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Open image in new window Figure 4 Helix-20 in EBOV NP core indicates an essential hydrophobic pocket.
Converging evidence indicates an essential role of glutamatergic neurotransmission in psychiatric diseases with pronounced deficits in empathy.
The gene knockdown of prp2 indicates an essential biological function for the zebrafish ortholog with a morphant phenotype that suggests a neurodegenerative action and gene expression effects which are apoptosis related and effects gene networks controlling neurogenesis and embryo development.
Evolutionary conservation indicates an essential role for these structures in the cell.
These mice develop hypertension in part via functional changes to VSMC and this indicates an essential role of Rap1 (and possibly Epac) in maintaining normal vascular physiology.
On the other hand, investigation concerning certain fibrotic diseases using Smad3-null mice indicates an essential role of Smad3 in EMT (95).
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These results indicate an essential role for proteins of the hnRNP complex in the splicing of mRNA precursors.
The obtained results indicate an essential intensification of ignition and combustion processes in the microwave burner compared to those in conventional burners.
RNA interference-mediated silencing of the messenger from Lamr in P. vannamei led to shrimp mortality and indicated an essential function of Lamr for shrimp viability.
Overall, these findings indicate an essential role for the adipose tissue during critical illness but also suggest that different processes are ongoing in lean vs. overweight/obese critically ill patients.
Furthermore, transient activation of YAP may reprogram Lgr5+ ISCs by partial inhibiting the Wnt pathway, which prevents ISCs from differentiating into Paneth cells and drives a pro-regenerative program through activation of the EGFR signaling pathway (Gregorieff et al., 2015), indicating an essential role for YAP (and TAZ) in intestinal regeneration.
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