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"Although this is primarily due to patent expirations, the flurry of negative guidance in '01 indicates a reduced ability to manage that predictable problem," Seiden wrote.
We do not think that this invalidates our model, as the SKAP read-out just indicates a reduced stability and higher dynamics of kinetochore-microtubules on both sides of the sister-kinetochores, consistent with the fact that these kinetochores are over time moving and correcting their position towards the middle of the spindle.
Moreover, the trend towards a lower metabolite ratio as calculated by ([homovanillic acid] + [DOPAC]) / [dopamine] in the fasudil treatment group (9.76 ± 3.14) versus MPTP control treatment (12.94 ± 3.64) indicates a reduced dopamine turnover and thus decreased cellular stress with fasudil (Fig. 6F).
It has been shown that the 677T variant increases the plasma homocysteine concentration in humans and reduces DNA methylation in cancer patients, which indicates a reduced synthesis of methionine and a more limited availability of the methyl donor, S-adenosyl-methionine, in the presence of the low activity T allele [ 5, 10].
Contrary to general expectation, differential scanning calorimetry of the deformed material indicates a reduced free volume.
It is especially the site 'Forest' that indicates a reduced diurnal range under drought conditions of 0.54 (± 0.25) MPa.
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The relatively low pristine/phytane ratio (low pr/ph ratio) indicates a reducing source (Hunt 1995).
Semi-saline water and iron-rich conditions are favorable for pyrite formation, and the appearance of pyrite in the study section indicates a reducing environment.
Austin's climate effectively prohibited such a late date, and this year the Games coincided with the start of the N.B.A. finals and the Stanley Cup, in early June, a shift in programming that some action-sports partisans took as a slight, indicating a reduced commitment on ESPN's part, after a difficult 2013.
Systemic exposure of CMS and colistin was significantly lower after nebulization compared to intravenous infusion [6, 45], indicating a reduced risk of nephrotoxicity [47].
HDL-c/TC ratio greater than 0.3 and LDL-c/HDL-c ratio less than 2.3 indicate a reduced risk of peripheral arterial disease [32].
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