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In addition, loss of HSF2 expression across many human malignancies indicates a fundamental role in tumorigenesis, which deserves future exploration.
The present study indicates a fundamental role of c- myc in the apoptosis of ALL cells, since spontaneous cell death occurred in vitro only in those cells that displayed elevated c- myc levels.
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We used R. solanacearum as a model because of the evidence indicating a fundamental role of HGT in this plant pathogen's evolution.
Accumulating evidence indicate a fundamental role of the early soluble oligomeric species of Aβ, rather than the mature fibrillar species, in the pathogenesis of AD [11] [15].
Murine embryos deficient in PRMT1 fail to develop, indicating a fundamental role for the protein, but Prmt1−/− cells are viable [32].
One cognitive cycle would therefore take 260 390 ms. The LIDA timing model is consistent with brain evidence indicating a fundamental role for a theta-gamma wave, spreading forward from sensory cortices to rostral corticothalamic regions.
We observe that the dimer is the most potent form for eliciting robust neutrophil recruitment, that the monomer is less potent and shows low sustained recruitment, and that the WT alone shows sustained and steady levels of recruitment, indicating a fundamental role for monomers and dimers in regulating recruitment (Figures 1 and 2).
These observations indicate a fundamental role for impaired barrier function in the susceptibility of Gpa33 –/– mice to a range of related inflammatory intestinal pathologies.
The low level of etv7 expression in multiple tissues might indicate a fundamental role of etv7 during both development and adulthood.
The primary function of this enzyme in fission yeast in the maintenance of genome stability appears to be due to its E3 ubiquitin ligase activity and the HIRAN domain, indicating a fundamental role for PCNA modification in preserving genomic integrity.
It indicates a fundamental relationship whose reality is as ancient as man's history.
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