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Mechanistic studies indicated that activation of PPAR γ interferes with the activities of the transcription factors activation protein 1 (and) anuclearear factor- κB (NF- κB)(Ricote et al, 2000).
These findings are in agreement with previous results [17] where the authors indicated that activation of PKC and its binding to RACK1 is not enough to activate JNK, and that a second stimulus is required in the MKK4/7 pathway [17].
This experiment indicated that activation of cellular kinases by oxidative stress may contribute to induction of intestinal UGT1A1.
Smoothing of the enveloping cell layer at the midblastula transition occurred normally and expression of bon/mixer and mezzo, zygotic transcription factors indicated that activation of the zygotic genome did occur.
Initial studies by Matherne and colleagues indicated that activation of the A1 adenosine receptor protects from myocardial ischemia [34].
These results indicated that activation of serotonin production is involved in the establishment of effective disease defenses in rice.
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Our data indicates that activation of peroxisome proliferator-activated receptors would increase UGT1A1 expression, resulting in reduction of serum bilirubin levels in human infants.
Several lines of evidence now indicate that activation of RAS-mitogen-activated protein (MAP) kinase pathways can generate increased ROS.
These results indicate that activation of TRPV1 increases transmitter release by activating presynaptic receptors expressed in central sensory nerve terminals.
Collectively these studies indicate that activation of apoptotic signalling cascade may not be the sole activity of BH3 mimetics.
These data indicate that activation of FOXO transcription factors further enhances resveratrol-induced FOXO transcriptional activity.
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