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A substantial decrease in claspin expression indicated loss of checkpoint-mediated ATR control of the cell cycle following DNA damage.
Reduction of peaks at 714, 937, and 1514 cm−1 indicated loss of aromaticity of metabolites (Fig. 4b).
This phenomenon was also verified by profilometry, which indicated loss of several hundred nanometers in film thickness after laser modification.
X-ray diffraction studies indicated loss of crystallinity and/or solubilisation of ezetimibe in the self-nanoemulsifying granules.
Cell counts guided by design-based stereology indicated loss of ~ 40% of neurons in WT hemorrhagic striata at one week, which was decreased by half in transgenics; no significant differences in microglia or astrocyte numbers were observed.
Values were adjusted for signs in such a way that positive Z-scores indicated gain of somatosensory function when the patient was more sensitive to the tested stimuli compared with controls (hyperesthesia, hyperalgesia, allodynia), and negative Z-scores indicated loss of function, referring to a lower sensitivity of the patient (hypoesthesia, hypoalgesia) [19].
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1) lower-case letters (el, e3 and e4) indicate loss-of-function alleles at each locus, collectively.
The resultant colonies were also confirmed to be ampicillin-sensitive, indicating loss of pMHM199.
A score above 1.96 indicates a gain in somatosensory function and a score below−1.96 indicates loss of somatosensory function.
Mitochondria seem to play a role in it with data indicating loss of function due to high intracellular ROS levels.
Neither TGFβ-dependent nor endogenously phosphorylated Smad2/3 was detectable in comparable amounts in transdifferentiated MFB, indicating loss of TGFβ sensitivity.
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